It’s all about the interactions! Our lab focuses on exploring cellular communication between immune cells and tissue resident cells, by using state-of the art single-cell RNA sequencing technologies. We are eager to reveal the consequences of immune-controlled cellular interactions on tissue physiological development and tissue–specific pathologies, specifically cancer. We combine experimental mouse models, advanced genomic technologies and computational analysis, together with study of clinical samples, in order to expand our understanding on developmental pathologies and mechanisms of cancer induction, progression, immune suppression in the tumor microenvironment and metastatic sites.